*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UV9058450 CHEMICAL NAME : 4,6(1H,5H)-Pyrimidinedione, dihydro-5-ethyl-5-phenyl-, and 5-ethyl-5-phenylbarbituric acid LAST UPDATED : 198910 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H14-N2-O2.C12-H12-N2-O3 MOLECULAR WEIGHT : 450.54 COMPOUND DESCRIPTOR : Drug Reproductive Effector Human SYNONYMS/TRADE NAMES : * Phenobarbitone and primidone * Primidone and phenobarbitone *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE : 3780 mg/kg SEX/DURATION : female 1-39 week(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - physical REFERENCE : APSVAM Acta Paediatrica Scandinavica. (Almqvist & Wiksell International, POB 4627, S-11691 Stockholm, Sweden) V.54-80 1965-91 For publisher information, see APAEEL Volume(issue)/page/year: 65,617,1976 *** END OF RECORD ***