*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV9282000
CHEMICAL NAME           : 5-Pyrimidinemethanol,
                          alpha-(2,4-dichlorophenyl)-alpha-phenyl-
CAS REGISTRY NUMBER     : 26766-27-8
BEILSTEIN REFERENCE NO. : 0756381
REFERENCE               : 5-23-12-00538 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H12-Cl2-N2-O
MOLECULAR WEIGHT        : 331.21
WISWESSER LINE NOTATION : T6N CNJ EXQR&R BG DG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
SYNONYMS/TRADE NAMES :
   * alpha-(2,4-Dichlorophenyl)-alpha-phenyl-5-pyrimidinemethanol
   * EL-273
   * Triarimol
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 525 mg/kg/14D-C
TOXIC EFFECTS :
   Liver - other changes
   Liver - changes in liver weight
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation,
   etc.)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   35,413,1976
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 50 ppm
REFERENCE :
   RSTUDV Rivista di Scienza e Technologia degli Alimenti e di Nutrizione
   Umana.  Review of Science and Technology of Food and Human Nutrition.
   (Bologna, Italy)  V.5-6, 1975-76.  Discontinued.  Volume(issue)/page/year:
   6,161,1976
 
                            *** END OF RECORD ***