*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW8000000
CHEMICAL NAME           : 2H-Pyrimido(1,6-b)(1,2,4)triazin-2-one,
                          1,6-dihydro-8-amino-3-methyl-1-(phenylmethyl)-6-
                          thioxo-
CAS REGISTRY NUMBER     : 119294-04-1
BEILSTEIN REFERENCE NO. : 5979050
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H13-N5-O-S
MOLECULAR WEIGHT        : 299.38
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,6-Dihydro-8-amino-3-methyl-1-(phenylmethyl)-6-thioxo-2H-pyrimido(1,6-b
     )(1,2,4)triazin-2-one
   * 2-Methyl-3-oxo-4-benzyl-6-amino-8-thioxopyrimido(3,4-b)-1,2,4-triazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 22,529,1988
 
                            *** END OF RECORD ***