*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UX1915000
CHEMICAL NAME           : Pyrocatechol, 4-methyl-
CAS REGISTRY NUMBER     : 452-86-8
BEILSTEIN REFERENCE NO. : 0636512
REFERENCE               : 4-06-00-05878 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H8-O2
MOLECULAR WEIGHT        : 124.15
WISWESSER LINE NOTATION : QR BQ D1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1,2-Benzenediol, 4-methyl-
   * 3,4-Dihydroxytoluene
   * Homocatechol
   * Homopyrocatechol
   * 4-Methyl-1,2-benzenediol
   * p-Methylcatechol
   * 4-Methylcatechol
   * p-Methylpyrocatechol
   * 4-Methylpyrocatechol
   * Toluene-3,4-diol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg/51W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   49,5143,1989
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 300 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 135,109,1984
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mg/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   14,251,1981
 
                            *** END OF RECORD ***