*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UX9458500
CHEMICAL NAME           : 1H-Pyrrole,
                          2,3-dichloro-5-(6,8-dichloro-4H-1,3-benzodioxin-4-yl)
                          -4-nitro-, (-)-
CAS REGISTRY NUMBER     : 105888-54-8
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H6-Cl4-N2-O4
MOLECULAR WEIGHT        : 384.00
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AL-R2081
   *   (-)-2,3-Dichloro-5-(6,8-dichloro-4H-1,3-benzodioxin-4-yl)-4-nitro-1H-pyr
     role
   * 4,5-Dichloro-2-(6',8'-dichloro-4'-H-1,3-benzodioxin-4'-yl)-3-nitropyrrole
   * Dioxapyrrolomycin
   * LL-F42248-alpha
   * Pyrroxamycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 40,233,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 40,899,1987
 
                            *** END OF RECORD ***