*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UX9633500
CHEMICAL NAME           : 1H-Pyrrole-1-heptanoic acid,
                          beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylet
                          hyl)- 3-phenyl-4-((phenylamino)carbonyl)-, calcium
                          salt (2:1), (R-(R*,R*))-
CAS REGISTRY NUMBER     : 134523-03-8
LAST UPDATED            : 199606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C66-H70-F2-N4-O10.Ca
MOLECULAR WEIGHT        : 1157.48
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Atorvastatin calcium
   * CI-981
   * PD 134298-38A
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 50,387,1994
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1300 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 50,387,1994
 
                            *** END OF RECORD ***