*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY0742500
CHEMICAL NAME           : 1,2-Pyrrolidinedicarboxamide, N(sup
                          1)-(2-chloroethyl)-N(sup 1)-nitroso-, (S)-
CAS REGISTRY NUMBER     : 81965-44-8
BEILSTEIN REFERENCE NO. : 6221830
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H13-Cl-N4-O3
MOLECULAR WEIGHT        : 248.70
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (S)-N(sup 1)-(2-Chloroethyl)-N(sup  
   1)-nitroso-1,2-pyrrolidinedicarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 30,583,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 220 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,829,1982
 
                            *** END OF RECORD ***