*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UY0742500 CHEMICAL NAME : 1,2-Pyrrolidinedicarboxamide, N(sup 1)-(2-chloroethyl)-N(sup 1)-nitroso-, (S)- CAS REGISTRY NUMBER : 81965-44-8 BEILSTEIN REFERENCE NO. : 6221830 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H13-Cl-N4-O3 MOLECULAR WEIGHT : 248.70 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * (S)-N(sup 1)-(2-Chloroethyl)-N(sup 1)-nitroso-1,2-pyrrolidinedicarboxamide *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 140 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,583,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 220 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,829,1982 *** END OF RECORD ***