*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UY0745000 CHEMICAL NAME : 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, L- CAS REGISTRY NUMBER : 1148-11-4 LAST UPDATED : 199406 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C13-H15-N-O4 MOLECULAR WEIGHT : 249.29 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * Benzyloxycarbonylproline * Benzyloxycarbonyl-L-proline * N-Benzyloxycarbonylproline * 1-(Benzyloxycarbonyl)proline * Carbobenzoxy-L-proline * Carbobenzoxy-S-proline * N-Carbobenzoxy-L-proline * Carbobenzyloxy-L-proline * L-1,2-Pyrrolidinedicarboxylic acid 1-benzyl ester * 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (S)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 280 mg/kg SEX/DURATION : female 28 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - mouse DOSE : 280 ug/kg SEX/DURATION : female 28 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 *** END OF RECORD ***