*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UY0745100 CHEMICAL NAME : 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl 2-(1,2-dibromoethyl) ester CAS REGISTRY NUMBER : 64187-33-3 BEILSTEIN REFERENCE NO. : 0439986 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C15-H17-Br2-N-O4 MOLECULAR WEIGHT : 435.15 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * N-Carbobenzoxy-L-proline 1,2-dibromoethyl ester * 1,2-Pyrrolidinedicarboxylic acid, 2-(1,2-dibromoethyl) 1-(phenylmethyl) ester *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 225 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 280 mg/kg SEX/DURATION : female 28 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - mouse DOSE : 280 mg/kg SEX/DURATION : female 28 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 *** END OF RECORD ***