*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY1014040
CHEMICAL NAME           : 2,5-Pyrrolidinedione,
                          3-(4-chlorophenyl)-1-(3-methyl-2-pyridinyl)-
CAS REGISTRY NUMBER     : 89703-08-2
BEILSTEIN REFERENCE NO. : 5588187
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H13-Cl-N2-O2
MOLECULAR WEIGHT        : 300.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(4-Chlorophenyl)-1-(3-methyl-2-pyridinyl)-2,5-pyrrolidinedione
   * I 11
   * IL 11
   * N-3-Methylpyridyl-2-imide of 3-p-chlorophenylsuccinic acid
   * Succinimide, 2-(p-chlorophenyl)-N-(3-methyl-2-pyridyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 42,69,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3400 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   38,872,1983
 
                            *** END OF RECORD ***