*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY1925450
CHEMICAL NAME           : 1-Pyrrolidinepropanol,
                          alpha-cyclohexyl-alpha-phenyl-, hydrochloride, (+)-
CAS REGISTRY NUMBER     : 30953-83-4
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H29-N-O.Cl-H
MOLECULAR WEIGHT        : 323.95
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+)-alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride
   * (+)-Procyclidine hydrochloride
   * dextro-Procyclidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 69 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 10,383,1955
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 10,383,1955
 
                            *** END OF RECORD ***