*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CA0300000
CHEMICAL NAME           : Anistreplase
CAS REGISTRY NUMBER     : 81669-57-0
LAST UPDATED            : 199407
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Apsac
   * BRL 26921
   * Eminase
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 30 units/kg/4M-C
TOXIC EFFECTS :
   Cardiac - cardiomyopathy including infarction
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   306,896,1993
 
                            *** END OF RECORD ***