*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB2975100
CHEMICAL NAME           : Anthranilic acid, N-(2,6-dichloro-m-tolyl)-,
                          ethoxymethyl ester
CAS REGISTRY NUMBER     : 29098-15-5
BEILSTEIN REFERENCE NO. : 2894433
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C17-H17-Cl2-N-O3
MOLECULAR WEIGHT        : 354.25
WISWESSER LINE NOTATION : GR CG D1 BMR BVO1O2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, ethoxymethyl ester
   * 2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid ethoxymethyl ester
   * N-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl ester
   * Estere etossimetilico dell' acido N-(2,6-dicloro-m-tolil)antranilico
   * Ethoxymethyl N-(2,6-dichloro-m-tolyl)anthranilate
   * Etoclofene
   * Etofen
   * Terofenamate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 307 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - cough
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   115,41,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 274 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - cough
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   115,41,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 918 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   115,41,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   115,41,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6240 mg/kg/26W-I
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Blood - changes in leukocyte (WBC) count
   Related to Chronic Data - death
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   115,41,1976
 
                            *** END OF RECORD ***