*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB4584400
CHEMICAL NAME           : 4H-Anthra(1,2-b)pyran-4,7,12-trione,
                          2-(3,3'-dimethyl(2,2'-bioxiran)-3-yl)-11-hydroxy-5-
                          methyl-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D-ara
                          bino-hexopyranosyl)-1 0-(2,3,6-
                          trideoxy-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-he
                          xopyranosyl)-
CAS REGISTRY NUMBER     : 11048-97-8
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C41-H50-N2-O11
MOLECULAR WEIGHT        : 746.93
WISWESSER LINE NOTATION : T D6 B666 CV JV OV ROJ EQ M1 F- FT6OTJ B1 CQ DN1&1&
                          H- FT6OTJ B1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic B26158
   * B 26158
   * Crystalline antibiotic B 26,158
   * Hedamycin
   * NSC-70929
   * NSC-70929D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACHAX Antimicrobial Agents and Chemotherapy (1961-70).  (Ann Arbor, MI)
   1961-70.  For publisher information, see AMACCQ.  Volume(issue)/page/year:
   -,613,1966
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 mg/L
REFERENCE :
   APMBAY Applied Microbiology.  (Washington, DC)  V.1-30, 1953-75.  For
   publisher information, see AEMIDF.  Volume(issue)/page/year: 12,428,1964
 
                            *** END OF RECORD ***