*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB4594000
CHEMICAL NAME           : Anthra(1,9-cd)pyrazol-6(2H)-one,
                          7-hydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-((
                          2- hydroxyethyl)amino)ethyl)amino)-, dihydrochloride
CAS REGISTRY NUMBER     : 88303-61-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H27-N5-O4.2Cl-H
MOLECULAR WEIGHT        : 498.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bianthrazole dihydrochloride
   * Biantrazole dihydrochloride
   * CI 941
   * DUP 941
   * Losoxantrone hydrochloride
   * NSC-357885
   * PD 113785
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 21 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCPHDZ Cancer Chemotherapy and Pharmacology.  (Springer-Verlag New York,
   Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.1-    1978-
   Volume(issue)/page/year: 23,8,1989
 
                            *** END OF RECORD ***