*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CB7350000 CHEMICAL NAME : Anthraquinone, 1-((2-hydroxyethyl)amino)-4-(methylamino)- CAS REGISTRY NUMBER : 2475-46-9 BEILSTEIN REFERENCE NO. : 2060684 REFERENCE : 4-14-00-00462 (Beilstein Handbook Reference) LAST UPDATED : 199710 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C17-H16-N2-O3 MOLECULAR WEIGHT : 296.35 WISWESSER LINE NOTATION : L C666 BV IVJ DM2Q GM1 COMPOUND DESCRIPTOR : Primary Irritant SYNONYMS/TRADE NAMES : * Acetate Brilliant Blue 4B * Acetoquinone Light Pure Blue R * Altocyl Brilliant Blue B * Amacel Blue BNN * Amacel Brilliant Blue B * 9,10-Anthracenedione, 1-((2-hydroxyethyl)amino)-4-(methylamino)- * Artisil Blue BSQ * Calcosyn Sapphire Blue 2GS * Calcosyn Sapphire Blue R * Celanthrene Brilliant Blue * Celanthrene Brilliant Blue FFS * Celliton Blue FFR * Celliton Fast Blue FBBN * Celliton Fast Blue FFR * Celliton Fast Blue FFRN * Celliton Fast Blue FFRS * Celutate Blue BLT * Celutate Blue RNH * Celutate Brilliant Blue B * C.I. 61505 * Cibacet Blue BNG * Cibacet Blue F3R * Cibacet Brilliant Blue BG New * Cibacete Brilliant Blue BG New * C.I. Disperse Blue 3 * Cilla Fast Blue FFR * Diacelliton Fast Brilliant Blue B * Diacelliton Fast Brilliant Blue BF * Disperse Blue K * Disperse Blue 3 * Dispersive Blue K * Duranol Brilliant Blue B * Duranol Brilliant Blue BN * Duranol Printing Blue B * Eastman Blue BNN * Eastman Blue GBN * Fenacet Fast Blue FF * Fenacet Fast Blue FFN * 4-Hydroxyethylamino-1-methylaminoanthraquinone * Interchem Acetate Blue B * Interchem Acetate Blue NBN * Interchem Acetate Blue RBN * Interchem Acetate Blue WNBN * Kayalon Fast Blue FN * Lurafix Blue FFR * 1-MA-4OEAA * 1-Methylamino-4-ethanolaminoanthraquinone * 1-Methylamino-4-(beta-hydroxyethylamino)anthraquinone * 1-Methylamino-4-oxyethylaminoanthraquinone * Microsetile Blue FF * Microsetile Blue FFR * Miketon Brilliant Blue B * Mireton Brilliant Blue B * Modr Disperzni 3 * Modr Ostacetova P3R * Nacelan Blue KLT * Nyloquinone Pure Blue * Nyloquinone Pure Blue R * Perliton Blue FFR * Serinyl Hosiery Blue * Serinyl Hosiery Blue BG * Serisol Brilliant Blue BG * Serisol Brilliant Blue BP * Serisol Brilliant Blue FF * Setacyl Blue BN * Setacyl Blue FG * Setacyl Blue RF * Setacyl Brilliant Blue * Setacyl Brilliant Blue BG * Supracet Brilliant Blue BG * Transetile Blue P-FER *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/24H REACTION SEVERITY : Mild REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1325,1986 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1345 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - other changes in urine composition Skin and Appendages - dermatitis, other (after systemic exposure) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555340 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 21(12),27,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - other changes in urine composition Skin and Appendages - dermatitis, other (after systemic exposure) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555340 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S41,1996 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1245 mg/kg/5D-C TOXIC EFFECTS : Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555340 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2233 No. of Facilities: 192 (estimated) No. of Industries: 9 No. of Occupations: 13 No. of Employees: 4067 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2233 No. of Facilities: 1537 (estimated) No. of Industries: 24 No. of Occupations: 21 No. of Employees: 24466 (estimated) No. of Female Employees: 5439 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***