*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB7350000
CHEMICAL NAME           : Anthraquinone,
                          1-((2-hydroxyethyl)amino)-4-(methylamino)-
CAS REGISTRY NUMBER     : 2475-46-9
BEILSTEIN REFERENCE NO. : 2060684
REFERENCE               : 4-14-00-00462 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C17-H16-N2-O3
MOLECULAR WEIGHT        : 296.35
WISWESSER LINE NOTATION : L C666 BV IVJ DM2Q GM1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Acetate Brilliant Blue 4B
   * Acetoquinone Light Pure Blue R
   * Altocyl Brilliant Blue B
   * Amacel Blue BNN
   * Amacel Brilliant Blue B
   * 9,10-Anthracenedione, 1-((2-hydroxyethyl)amino)-4-(methylamino)-
   * Artisil Blue BSQ
   * Calcosyn Sapphire Blue 2GS
   * Calcosyn Sapphire Blue R
   * Celanthrene Brilliant Blue
   * Celanthrene Brilliant Blue FFS
   * Celliton Blue FFR
   * Celliton Fast Blue FBBN
   * Celliton Fast Blue FFR
   * Celliton Fast Blue FFRN
   * Celliton Fast Blue FFRS
   * Celutate Blue BLT
   * Celutate Blue RNH
   * Celutate Brilliant Blue B
   * C.I. 61505
   * Cibacet Blue BNG
   * Cibacet Blue F3R
   * Cibacet Brilliant Blue BG New
   * Cibacete Brilliant Blue BG New
   * C.I. Disperse Blue 3
   * Cilla Fast Blue FFR
   * Diacelliton Fast Brilliant Blue B
   * Diacelliton Fast Brilliant Blue BF
   * Disperse Blue K
   * Disperse Blue 3
   * Dispersive Blue K
   * Duranol Brilliant Blue B
   * Duranol Brilliant Blue BN
   * Duranol Printing Blue B
   * Eastman Blue BNN
   * Eastman Blue GBN
   * Fenacet Fast Blue FF
   * Fenacet Fast Blue FFN
   * 4-Hydroxyethylamino-1-methylaminoanthraquinone
   * Interchem Acetate Blue B
   * Interchem Acetate Blue NBN
   * Interchem Acetate Blue RBN
   * Interchem Acetate Blue WNBN
   * Kayalon Fast Blue FN
   * Lurafix Blue FFR
   * 1-MA-4OEAA
   * 1-Methylamino-4-ethanolaminoanthraquinone
   * 1-Methylamino-4-(beta-hydroxyethylamino)anthraquinone
   * 1-Methylamino-4-oxyethylaminoanthraquinone
   * Microsetile Blue FF
   * Microsetile Blue FFR
   * Miketon Brilliant Blue B
   * Mireton Brilliant Blue B
   * Modr Disperzni 3
   * Modr Ostacetova P3R
   * Nacelan Blue KLT
   * Nyloquinone Pure Blue
   * Nyloquinone Pure Blue R
   * Perliton Blue FFR
   * Serinyl Hosiery Blue
   * Serinyl Hosiery Blue BG
   * Serisol Brilliant Blue BG
   * Serisol Brilliant Blue BP
   * Serisol Brilliant Blue FF
   * Setacyl Blue BN
   * Setacyl Blue FG
   * Setacyl Blue RF
   * Setacyl Brilliant Blue
   * Setacyl Brilliant Blue BG
   * Supracet Brilliant Blue BG
   * Transetile Blue P-FER
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,1325,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1345 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Kidney, Ureter, Bladder - other changes in urine composition
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555340
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 21(12),27,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Kidney, Ureter, Bladder - other changes in urine composition
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555340
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 15(Suppl 1),S41,1996
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1245 mg/kg/5D-C
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - transaminases
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0555340

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 5 mg/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M2233
       No. of Facilities: 192 (estimated)
       No. of Industries: 9
       No. of Occupations: 13
       No. of Employees: 4067 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2233
       No. of Facilities: 1537 (estimated)
       No. of Industries: 24
       No. of Occupations: 21
       No. of Employees: 24466 (estimated)
       No. of Female Employees: 5439 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***