*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY5768800
CHEMICAL NAME           : 2-Pyrrolidinone, 1-ethenyl-, polymer with
                          2-methylene-1,3-propanediyl bis(methylcarbamate)
CAS REGISTRY NUMBER     : 68045-74-9
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : (C8-H14-N2-O4.C6-H9-N-O)x
SYNONYMS/TRADE NAMES :
   * BAY-I-7433
   * Copolymer of N-vinylpyrrolidone and 1,1-di(methylaminocarbonyloxymethyl)  
   ethylene
   * Copovithane
   * 1-Ethenyl-2-pyrrolidinone, polymer with 2-methylene-1,3-propanediyl  
   bis(methylcarbamate)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   7,621,1982
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   7,621,1982
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   7,621,1982
 
                            *** END OF RECORD ***