*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UY5770700
CHEMICAL NAME : 2-Pyrrolidinone, 5-ethyl-5-phenyl-, (+-)-
CAS REGISTRY NUMBER : 5556-57-0
BEILSTEIN REFERENCE NO. : 1451635
REFERENCE : 5-21-08-00152 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C12-H15-N-O
MOLECULAR WEIGHT : 189.28
WISWESSER LINE NOTATION : T5MVTJ E2 ER
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* (+-)-5-Ethyl-5-phenylpyrrolid-2-one
* (+-)-5-Ethyl-5-phenyl-2-pyrrolidinone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 25,790,1965
TYPE OF TEST : LD54 - Lethal Dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 812 mg/kg
TOXIC EFFECTS :
Behavioral - aggression
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 9,52,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 750 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle weakness
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 25,790,1965
*** END OF RECORD ***