*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY7545000
CHEMICAL NAME           : 3-Pyrrolin-2-one, 3-acetyl-4-hydroxy-
CAS REGISTRY NUMBER     : 2113-93-1
BEILSTEIN REFERENCE NO. : 0120803
REFERENCE               : 4-21-00-05715 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H7-N-O3
MOLECULAR WEIGHT        : 141.14
WISWESSER LINE NOTATION : T5MV EHJ CV1 DQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Acetyl-1,5-dihydro-4-hydroxy-2H-pyrrol-2-one
   * alpha-Acetyl-beta-hydroxy-delta(sup alpha,beta)-butyrolactam
   * 3-Acetyl-4-hydroxy-3-pyrrolin-2-one
   * 3-Acetyltetramic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 940 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,277,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - tetany
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,277,1961
 
                            *** END OF RECORD ***