*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY7759650
CHEMICAL NAME           : 1H-Pyrrolizine-5-acetic acid,
                          2,3-dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-
CAS REGISTRY NUMBER     : 156897-06-2
BEILSTEIN REFERENCE NO. : 6823674
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H22-Cl-N-O2
MOLECULAR WEIGHT        : 379.91
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2,3-Dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-ac
     etic acid
   *   2,2-Dimethyl-6-(4-chlorophenyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)
     acetic acid
   * ML 3000
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 45,159,1995
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1100 mg/kg/11D-I
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from duodenum
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1329,1994
 
                            *** END OF RECORD ***