*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY8000000
CHEMICAL NAME           : 1H-Pyrrolizine-3,5(2H,6H)-dione, dihydro-
CAS REGISTRY NUMBER     : 18356-28-0
BEILSTEIN REFERENCE NO. : 0121236
REFERENCE               : 5-21-10-00069 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C7-H9-N-O2
MOLECULAR WEIGHT        : 139.17
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CI 911
   * Dihydro-1H-pyrrolizine-3,5(2H,6H)-dione
   * 3,5-Dioxopyrrolizidine
   * 3H-Pyrrolizine-3,5(2H)-dione, tetrahydro-
   * Rolziracetam
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 7 gm/kg/14D-I
TOXIC EFFECTS :
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
   Musculoskeletal - other changes
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 17,545,1989
 
                            *** END OF RECORD ***