*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY8546000
CHEMICAL NAME           : 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one,
                          1,2,3,11a-tetrahydro-3,8-dihydroxy-7-methoxy-,
                          (3S-trans)-
CAS REGISTRY NUMBER     : 59593-16-7
LAST UPDATED            : 198309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H14-N2-O4.1/2H2-O
MOLECULAR WEIGHT        : 271.27
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic MC-916-A
   * MC-916-A
   * Neothramycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,188,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,188,1981
 
                            *** END OF RECORD ***