*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY9453210
CHEMICAL NAME           : 4H-Pyrrolo(3,2-d)pyrimidin-4-one,
                          1,5-dihydro-2-amino-7-(3-pyridinylmethyl)-
CAS REGISTRY NUMBER     : 133432-71-0
LAST UPDATED            : 199409
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H11-N5-O
MOLECULAR WEIGHT        : 241.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BCX-34
   *   1,5-Dihydro-2-amino-7-(3-pyridinylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-o
     ne
   * 9-(3-Pyridylmethyl)-7H-9-deazaguanine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   18,887,1993
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >88 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   18,887,1993
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   18,887,1993
 
                            *** END OF RECORD ***