*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UY9453220 CHEMICAL NAME : 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 1,5-dihydro-2-amino-7-(3-thienylmethyl)-, monohydrochloride,monohydrate LAST UPDATED : 199606 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H10-N4-O-S.Cl-H.H2-O MOLECULAR WEIGHT : 300.79 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-Amino-7-(3-thenyl)-1,5-dihydro-4H-pyrrolo(3,2-d)pyrimidin-4-one hydrochloride hydrate * CI 1000 * PD 141955-2 *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3500 mg/kg/2W-I TOXIC EFFECTS : Gastrointestinal - other changes Related to Chronic Data - death REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 28,51,1995 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1400 mg/kg/4W-I TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes in urine composition Kidney, Ureter, Bladder - changes in bladder weight REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 28,51,1995 *** END OF RECORD ***