*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UZ9550000
CHEMICAL NAME : Quinaldic acid, 4-hydroxy-8-methoxy-
CAS REGISTRY NUMBER : 2929-14-8
BEILSTEIN REFERENCE NO. : 0202789
REFERENCE : 4-22-00-02513 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C11-H9-N-O4
MOLECULAR WEIGHT : 219.21
WISWESSER LINE NOTATION : T66 BNJ CVQ EQ JO1
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* 4-Hydroxy-8-methoxyquinaldic acid
* 8-Methoxy-4-hydroxyquinoline-2-carboxylic acid
* 8-Methyl ether of xanthurenic acid
* Xanthurenic acid-8-methyl ether
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5280 mg/kg/44W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
Skin and Appendages - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
28,183,1968
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 89 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year:
11,212,1957
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 80 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year:
11,212,1957
*** END OF RECORD ***