*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VA0700000 CHEMICAL NAME : Quinaldinium, 1,1'-decamethylenebis(4-amino-, dichloride CAS REGISTRY NUMBER : 522-51-0 LAST UPDATED : 199603 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C30-H40-N4.2Cl MOLECULAR WEIGHT : 527.64 WISWESSER LINE NOTATION : T66 BKJ C1 EZ B10- BT66 BKJ C1 EZ &Q 2 &G 2 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * BAQD 10 * Decamethylenebis(4-aminoquinaldinium chloride) * 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) * 1,10-Decamethylene-bis(4-aminoquinaldinium chloride) * Decamine * Decamine (pharmaceutical) * Dekadin * Dekamin * Dequadin * Dequadin chloride * Dequafungan * Dequalinium chloride * Dequavagyn * Dequavet * Efisol * Eriosept * Evazol * Grocreme * Labosept * Optipect * Phylletten * Polycidine * Sorot *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18300 ug/kg TOXIC EFFECTS : Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 82,231,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 70 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1900 ug/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 90 mg/kg/15W-I TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 82,231,1993 *** END OF RECORD ***