*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VA0980000 CHEMICAL NAME : 4-Quinazolinamine, 6,7-dimethoxy-2-(4-thiomorpholinyl)-, monohydrochloride CAS REGISTRY NUMBER : 67958-70-7 LAST UPDATED : 199507 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C14-H18-N4-O2-S.Cl-H MOLECULAR WEIGHT : 342.88 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 6,7-Dimethoxy-2-(4-thiomorpholinyl)-4-quinazolinamine monohydrochloride * PD 88823 *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 16800 mg/kg/2W-C TOXIC EFFECTS : Blood - changes in bone marrow (not otherwise specified) Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 81,166,1985 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 27300 mg/kg/13W-C TOXIC EFFECTS : Blood - changes in bone marrow (not otherwise specified) Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 81,166,1985 *** END OF RECORD ***