*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA1352700
CHEMICAL NAME           : 8-Quinazolinecarboxylic acid,
                          3,4-dihydro-4-oxo-3-(2-pyridyl)-2,6,7-trimethyl-
CAS REGISTRY NUMBER     : 86542-78-1
BEILSTEIN REFERENCE NO. : 5986321
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H15-N3-O3
MOLECULAR WEIGHT        : 309.35
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,4-Dihydro-4-oxo-3-(2-pyridyl)-2,6,7-trimethyl-8-quinazolinecarboxylic  
   acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1422,1983
 
                            *** END OF RECORD ***