*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA2380000
CHEMICAL NAME           : 4(3H)-Quinazolinone, 3-benzyl-2-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 3244-93-7
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H14-N2-O.Cl-H
MOLECULAR WEIGHT        : 286.78
WISWESSER LINE NOTATION : T66 BVN ENJ C1R& D1 &GH
SYNONYMS/TRADE NAMES :
   * CHI 2
   * 2-Methyl-3-benzylchinazolon-4 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   13,591,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,626,1973
 
                            *** END OF RECORD ***