*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA3280000
CHEMICAL NAME           : 4(1H)-Quinazolinone,
                          2,3-dihydro-1-(piperidinoacetyl)-3-(p-tolyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 20887-16-5
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H25-N3-O2.Cl-H
MOLECULAR WEIGHT        : 399.96
WISWESSER LINE NOTATION : T66 BVN EN DHJ CR D1& EV1- AT6NTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3-Dihydro-1-(piperidinoacetyl)-3-(p-tolyl)-4(1H)-quinazolinone  
   hydrochloride
   * 1-Piperidinoacetyl-3-(4-methylphenyl)-2,3-dihydro-4(1H)-quinazolinone  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,1136,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 9,639,1974
 
                            *** END OF RECORD ***