*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA9613000
CHEMICAL NAME           : 2-Quinolineacrylic acid,
                          2-(4-(p-chlorophenyl)-1-piperazinyl)ethyl ester
LAST UPDATED            : 199212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H24-Cl-N3-O2
MOLECULAR WEIGHT        : 421.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Piperazineethanol, 4-(p-chlorophenyl)-, 2-quinolineacrylate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3200 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 55,290,1966
 
                            *** END OF RECORD ***