*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA3100333
CHEMICAL NAME           : 2(1H)-Quinazolinone,
                          1-(cyclopropylmethyl)-6-methoxy-4-phenyl-
CAS REGISTRY NUMBER     : 33453-23-5
BEILSTEIN REFERENCE NO. : 0761592
REFERENCE               : 5-25-02-00213 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H18-N2-O2
MOLECULAR WEIGHT        : 306.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ciproquazone
   * 1-(Cyclopropylmethyl)-6-methoxy-4-phenyl-2(1H)-quinazolinone
   * SL 573
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg/30D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Related to Chronic Data - changes in testicular weight
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 13,1991,1979
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9100 mg/kg/13W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in bladder weight
   Blood - changes in erythrocyte (RBC) count
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 13,1991,1979
 
                            *** END OF RECORD ***