*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VB1993650 CHEMICAL NAME : 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6 -fluoro- 4-oxo- CAS REGISTRY NUMBER : 93106-60-6 BEILSTEIN REFERENCE NO. : 5307824 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C19-H22-F-N3-O3 MOLECULAR WEIGHT : 359.44 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Baytril * BAY VP 2674 * CFPQ * 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-qui nolinecarboxylic acid * Enrofloxacin *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4336 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 60 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 248,135,1991 *** END OF RECORD ***