*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : VB8400000
CHEMICAL NAME : Quinoline, 3-fluoro-4-nitro-, 1-oxide
CAS REGISTRY NUMBER : 17576-63-5
BEILSTEIN REFERENCE NO. : 1315880
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C9-H5-F-N2-O3
MOLECULAR WEIGHT : 208.16
WISWESSER LINE NOTATION : T66 BNJ BO DF ENW
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* 3-Fluoro-4-nitroquinoline 1-oxide
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 347 mg/kg/I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 17,544,1969
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 10 umol/L
REFERENCE :
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75,
1907-84. For publisher information, see JJCREP. Volume(issue)/page/year:
60,155,1969
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - rat Ascites tumor
DOSE/DURATION : 100 nmol/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring
St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year:
17,31,1975
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION : 2 umol/L
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 229,416,1971
*** END OF RECORD ***