*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB8925000
CHEMICAL NAME           : Quinoline, 4-(hydroxyamino)-6-methyl-, 1-oxide
CAS REGISTRY NUMBER     : 13442-08-5
BEILSTEIN REFERENCE NO. : 0393342
REFERENCE               : 5-22-14-00477 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H10-N2-O2
MOLECULAR WEIGHT        : 190.22
WISWESSER LINE NOTATION : T66 BNJ BO EMQ H1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4-(Hydroxyamino)-6-methylquinoline 1-oxide
   * 6-Methyl-4-hydroxylaminoquinoline 1-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg/50D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   16,631,1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5100 ug/L
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 24,1245,1968
 
                            *** END OF RECORD ***