*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC0550000
CHEMICAL NAME           : Quinoline, 6-methyl-
CAS REGISTRY NUMBER     : 91-62-3
BEILSTEIN REFERENCE NO. : 0110336
REFERENCE               : 5-20-07-00400 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C10-H9-N
MOLECULAR WEIGHT        : 143.20
WISWESSER LINE NOTATION : T66 BNJ H1
COMPOUND DESCRIPTOR     : Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * p-Methylquinoline
   * 6-Methylquinoline
   * p-Toluquinoline
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Moderate
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,871,1979
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 28(12),56,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 386 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,871,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,871,1979
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 25 ug/plate
REFERENCE :
   APTOD9 Abstracts of Papers, Society of Toxicology.  Annual Meetings.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
   Volume(issue)/page/year: 19,A105,1980

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***