*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB2600000
CHEMICAL NAME           : Quinoline,
                          7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-3-
                          methyl-
CAS REGISTRY NUMBER     : 85-10-9
BEILSTEIN REFERENCE NO. : 0031383
REFERENCE               : 4-22-00-04796 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H28-Cl-N3
MOLECULAR WEIGHT        : 333.95
WISWESSER LINE NOTATION : T66 BNJ D EMY&3N2&2 IG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-3-methylquinoline
   * Nivaquine C
   * 1,4-Pentanediamine, N4-(7-chloro-3-methyl-4-quinolinyl)-N1,N1-diethyl-
   * RP 3038
   * SN 6911
   * Sontochin
   * Sontoquine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 100,408,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
                            *** END OF RECORD ***