*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC3537000
CHEMICAL NAME           : Quinolinium,
                          2-(N-(p-(bis(2-chloroethyl)amino)phenyl)formimidoyl)-
                          1-methyl-, chloride
CAS REGISTRY NUMBER     : 25843-64-5
LAST UPDATED            : 198909
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H22-Cl2-N3.Cl
MOLECULAR WEIGHT        : 422.81
WISWESSER LINE NOTATION : T66 BKJ B1 C1UMR DN2G2G &G
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * IMET 3106
   * Quinolinium,  
   2-(((4-(bis(2-chloroethyl)amino)phenyl)imino)methyl)-1-methyl-, chloride
   * Zimet 3106
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 125 mg/kg
SEX/DURATION            : female 7-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   110,1067,1971
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 188 mg/kg
SEX/DURATION            : female 7-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
   Laboratoriums-diagnostik.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
   18, 102 Berlin, Ger. Dem. Rep.)  V.109-    1970-  Volume(issue)/page/year:
   110,1067,1971
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 125 mg/kg
SEX/DURATION            : female 7-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,122,1972
 
                            *** END OF RECORD ***