*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VC3537000 CHEMICAL NAME : Quinolinium, 2-(N-(p-(bis(2-chloroethyl)amino)phenyl)formimidoyl)- 1-methyl-, chloride CAS REGISTRY NUMBER : 25843-64-5 LAST UPDATED : 198909 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H22-Cl2-N3.Cl MOLECULAR WEIGHT : 422.81 WISWESSER LINE NOTATION : T66 BKJ B1 C1UMR DN2G2G &G COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * IMET 3106 * Quinolinium, 2-(((4-(bis(2-chloroethyl)amino)phenyl)imino)methyl)-1-methyl-, chloride * Zimet 3106 *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 125 mg/kg SEX/DURATION : female 7-11 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 110,1067,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 188 mg/kg SEX/DURATION : female 7-11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 110,1067,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 125 mg/kg SEX/DURATION : female 7-11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,122,1972 *** END OF RECORD ***