*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC3656000
CHEMICAL NAME           : Quinolinium,
                          1,1'-((1,4-dioxo-1,4-butanediyl)bis(oxy-2,1-ethanediy
                          l))bis-, diiodide
CAS REGISTRY NUMBER     : 56583-56-3
LAST UPDATED            : 198408
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C26-H26-N2-O4.2I
MOLECULAR WEIGHT        : 684.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chinotilin
   * Khinotilin
   * Quinotiline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EKFMA7 Eksperimental'naya i Klinicheskaya Farmakoterapiya.  (Izdatel'stvo
   Zinantne, Riga, USSR) No.1-    1970-  Volume(issue)/page/year: 11,111,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5600 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   EKFMA7 Eksperimental'naya i Klinicheskaya Farmakoterapiya.  (Izdatel'stvo
   Zinantne, Riga, USSR) No.1-    1970-  Volume(issue)/page/year: 11,111,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,164,1982
 
                            *** END OF RECORD ***