*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC5600000
CHEMICAL NAME           : 8-Quinolinol, 5,7-dichloro-2-methyl-
CAS REGISTRY NUMBER     : 72-80-0
BEILSTEIN REFERENCE NO. : 0156683
REFERENCE               : 5-21-03-00346 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C10-H7-Cl2-N-O
MOLECULAR WEIGHT        : 228.08
WISWESSER LINE NOTATION : T66 BNJ C1 GG IG JQ
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Chloroquinaldol
   * Chlorquinaldol
   * 5,7-Dichloro-8-hydroxyquinaldine
   * 5,7-Dichloro-2-methyl-8-hydroxyquinoline
   * 5,7-Dichloro-2-methyl-8-quinolinol
   * 5,7-Dichloro-8-quinaldinol
   * Gyno-sterosan
   * Hydroxydichloroquinaldine
   * Siasteran
   * Siogene
   * Siosteran
   * Sterosan
   * Steroxin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 660 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,33,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 2250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,33,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,33,1969
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,159,1974
 
                            *** END OF RECORD ***