*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VH2100000
CHEMICAL NAME           : Resorcinol, 5-methyl-
CAS REGISTRY NUMBER     : 504-15-4
BEILSTEIN REFERENCE NO. : 1071903
REFERENCE               : 4-06-00-05892 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 15
MOLECULAR FORMULA       : C7-H8-O2
MOLECULAR WEIGHT        : 124.15
WISWESSER LINE NOTATION : QR CQ E1
SYNONYMS/TRADE NAMES :
   * 1,3-Dihydroxy-5-methylbenzene
   * 3,5-Dihydroxytoluene
   * 5-Methyl-1,3-benzenediol
   * 5-Methylresorcin
   * 5-Methylresorcinol
   * Orcin
   * Orcinol
   * Orcinol, 5-methylresorcinol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 844 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPPAF Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR.  Labor
   Hygiene and Occupational Pathology in the Estonian SSR.  (Institut
   Eksperimental'noi i Klinicheskoi Meditsiny Ministerstva Zdravookhraneniya
   Estonskoi SSR, Tallinn, USSR)  V.8-    1972-  Volume(issue)/page/year:
   8,145,1972
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   RMSRA6 Revue Medicale de la Suisse Romande.  (Societe Medicale de La Suisse
   Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland)  V.1-    1881-
   Volume(issue)/page/year: 15,561,1895
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 844 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPPAF Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR.  Labor
   Hygiene and Occupational Pathology in the Estonian SSR.  (Institut
   Eksperimental'noi i Klinicheskoi Meditsiny Ministerstva Zdravookhraneniya
   Estonskoi SSR, Tallinn, USSR)  V.8-    1972-  Volume(issue)/page/year:
   8,145,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 772 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   34(4-6),16,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 405 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 12,410,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 290 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 12,410,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   34(4-6),16,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1687 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   34(4-6),16,1969
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   RMSRA6 Revue Medicale de la Suisse Romande.  (Societe Medicale de La Suisse
   Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland)  V.1-    1881-
   Volume(issue)/page/year: 15,561,1895
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RMSRA6 Revue Medicale de la Suisse Romande.  (Societe Medicale de La Suisse
   Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland)  V.1-    1881-
   Volume(issue)/page/year: 15,561,1895
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),16,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 7800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),16,1980
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8210 mg/kg/35W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes in urine composition
   Endocrine - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 34(4),14,1969

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M0834
       No. of Facilities: 81 (estimated)
       No. of Industries: 2
       No. of Occupations: 7
       No. of Employees: 1847 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***