*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VJ2247500
CHEMICAL NAME           : beta-D-Ribofuranuronic acid,
                          1-(6-amino-9H-purin-9-yl)-1-deoxy-, ethyl ester
CAS REGISTRY NUMBER     : 35803-57-7
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H15-N5-O5
MOLECULAR WEIGHT        : 309.32
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A-40557
   * Abbott 40557
   * 1-(6-Amino-9H-purin-9-yl)-1-deoxy-beta-D-ribofuranuronic acid ethyl ester
   * Ethyl adenosine-5'-carboxylate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 16,132,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,1306,1973
 
                            *** END OF RECORD ***