*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VJ6200000
CHEMICAL NAME           : Rifamycin SV,
                          3-((6-ethyl-1,4-diazabicyclo(4.4.0)decyl)iminomethyl)
                          -
CAS REGISTRY NUMBER     : 122188-46-9
LAST UPDATED            : 199406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C48-H66-N4-O12
MOLECULAR WEIGHT        : 891.18
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CGP 29861
   * 3-((6-Ethyl-1,4-diazabicyclo(4.4.0)decyl)iminomethyl)rifamycin SV
   * 3-(1-Iminomethyl-6-ethyl-1,4-diazabicyclo(4.4.0)decyl)rifamycin SV
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,845,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   13,845,1988
 
                            *** END OF RECORD ***