*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : VL0457000
CHEMICAL NAME : Rose oil
CAS REGISTRY NUMBER : 8007-01-0
LAST UPDATED : 199701
DATA ITEMS CITED : 9
COMPOUND DESCRIPTOR : Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* Attar rose
* Attar of rose
* Essence of rose
* Oil of rose
* Oil of rose blossom
* Oil of rose bulgarian
* Otto rose
* Otto of rose
* Rose de grasse
* Rose de mai
* Rosen oel
* Rosenol
* Rose oil bulgarian
* Rose otto
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 12,979,1974
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2975 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis
Behavioral - coma
Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
MBIID4 MBI, Mediko Biologicheskaya Informatsiya. Medical-Biological
Information. ("Ivana Vazova" No. 3, Sofia 1000, Bulgaria) 1967-
Volume(issue)/page/year: (3),8,1988
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1045 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MBIID4 MBI, Mediko Biologicheskaya Informatsiya. Medical-Biological
Information. ("Ivana Vazova" No. 3, Sofia 1000, Bulgaria) 1967-
Volume(issue)/page/year: (3),8,1988
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 12,979,1974
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12750 mg/kg/30D-I
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Blood - normocytic anemia
Liver - other changes
REFERENCE :
MBIID4 MBI, Mediko Biologicheskaya Informatsiya. Medical-Biological
Information. ("Ivana Vazova" No. 3, Sofia 1000, Bulgaria) 1967-
Volume(issue)/page/year: (3),8,1988
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12750 mg/kg/6W-I
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - changes in testicular weight
REFERENCE :
MBIID4 MBI, Mediko Biologicheskaya Informatsiya. Medical-Biological
Information. ("Ivana Vazova" No. 3, Sofia 1000, Bulgaria) 1967-
Volume(issue)/page/year: 3,8,1988
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 82966
No. of Facilities: 530 (estimated)
No. of Industries: 3
No. of Occupations: 22
No. of Employees: 29197 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 82966
No. of Facilities: 910 (estimated)
No. of Industries: 4
No. of Occupations: 7
No. of Employees: 12400 (estimated)
No. of Female Employees: 8636 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***