*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VM1170000 CHEMICAL NAME : Rubus ellipticus Smith, extract excluding roots SUBSTANCE DEFINITION : Plant belonging to the family Rosaceae REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- LAST UPDATED : 199506 DATA ITEMS CITED : 4 COMPOUND DESCRIPTOR : Reproductive Effector Natural Product SYNONYMS/TRADE NAMES : * Hinsalu * Zardanchu *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) REFERENCE : IJSIDW Indian Journal of Pharmaceutical Sciences. (Kalina, Santa Cruz (East), Bombay 400 029, India) V.40(2)- 1978- Volume(issue)/page/year: 52,174,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IJCREE International Journal of Crude Drug Research. (Swets & Zeitlinger B.V., POB 825, 2160 SZ Lisse, Netherlands) V.20- 1982- Volume(issue)/page/year: 21,183,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - body temperature decrease REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 9,91,1971 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 350 mg/kg SEX/DURATION : female 1-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : IJCREE International Journal of Crude Drug Research. (Swets & Zeitlinger B.V., POB 825, 2160 SZ Lisse, Netherlands) V.20- 1982- Volume(issue)/page/year: 21,183,1983 *** END OF RECORD ***