*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VO1625000
CHEMICAL NAME           : Salicylic acid, amino-, ethyl ester
CAS REGISTRY NUMBER     : 6059-17-2
BEILSTEIN REFERENCE NO. : 2092242
REFERENCE               : 4-14-00-01974 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H11-N-O3
MOLECULAR WEIGHT        : 181.21
WISWESSER LINE NOTATION : ZR CQ DVO2
SYNONYMS/TRADE NAMES :
   * p-Aminosalicylic acid ethyl ester
   * Benzoic acid, 4-amino-2-hydroxy-, ethyl ester
   * Ethyl 4-amino-2-hydroxybenzoate
   * Ethyl p-aminosalicylate
   * Pas aethyl ester
   * Pas ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
   Liver - other changes
   Blood - changes in spleen
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 11,139T,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 2,112,1952
 
                            *** END OF RECORD ***