*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VO1638000
CHEMICAL NAME           : Salicylic acid, 4-amino-, hydrazide
CAS REGISTRY NUMBER     : 6946-29-8
BEILSTEIN REFERENCE NO. : 2965831
REFERENCE               : 4-14-00-01995 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H9-N3-O2
MOLECULAR WEIGHT        : 167.19
WISWESSER LINE NOTATION : ZMVR DZ BQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-2-hydroxybenzoic acid hydrazide
   * p-Aminosalicylic acid hydrazide
   * Apacizin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
                            *** END OF RECORD ***