*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VO1870000
CHEMICAL NAME           : Salicylic acid, 5-bromo-, acetate
CAS REGISTRY NUMBER     : 1503-53-3
BEILSTEIN REFERENCE NO. : 2695058
REFERENCE               : 2-10-00-00064 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H7-Br-O4
MOLECULAR WEIGHT        : 259.07
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetyl 5-bromosalicylic acid
   * 2-(Acetyloxy)-5-bromobenzoic acid
   * Benzoic acid, 2-(acetyloxy)-5-bromo-
   * 5-Bromoacetylsalicylic acid
   * Bromoaspirin
   * 5-Bromosalicylic acid acetate
   * Sedasprin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1130 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 25,221,1946
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 25,221,1946
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16800 mg/kg/8W-C
TOXIC EFFECTS :
   Musculoskeletal - other changes
   Related to Chronic Data - death
REFERENCE :
   CRAAA7 Current Researches in Anesthesia and Analgesia.  (Cleveland, OH)
   V.1-35, 1922-56.  For publisher information, see AACRAT.
   Volume(issue)/page/year: 25,221,1946
 
                            *** END OF RECORD ***