*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VO4375000
CHEMICAL NAME           : Salicylic acid, isopentyl ester
CAS REGISTRY NUMBER     : 87-20-7
BEILSTEIN REFERENCE NO. : 2580465
REFERENCE               : 4-10-00-00153 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C12-H16-O3
MOLECULAR WEIGHT        : 208.28
WISWESSER LINE NOTATION : QR BVO2Y1&1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Isoamylester kyseliny salicylove
   * Isoamyl o-hydroxybenzoate
   * Isoamyl salicylate
   * Isopentyl-2-hydroxyphenyl methanoate
   * Isopentyl salicylate
   * 3-Methylbutyl 2-hydroxybenzoate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3300 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (2),25,1994
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2480 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (2),25,1994
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 43 gm/kg/13W-C
TOXIC EFFECTS :
   Behavioral - fluid intake
   Kidney, Ureter, Bladder - urine volume increased
   Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,185,1975
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 12600 mg/kg
SEX/DURATION            : male 42 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,185,1975

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1608
       No. of Facilities: 186 (estimated)
       No. of Industries: 4
       No. of Occupations: 20
       No. of Employees: 5116 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1608
       No. of Facilities: 7395 (estimated)
       No. of Industries: 42
       No. of Occupations: 48
       No. of Employees: 73285 (estimated)
       No. of Female Employees: 34267 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***