*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VO4395500 CHEMICAL NAME : Salicylic acid, isopropyl ester, O-ester with O-ethyl isopropylphosphoramidothioate CAS REGISTRY NUMBER : 25311-71-1 OTHER CAS REGISTRY NOS. : 61711-63-5 BEILSTEIN REFERENCE NO. : 2949615 LAST UPDATED : 199710 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C15-H24-N-O4-P-S MOLECULAR WEIGHT : 345.43 WISWESSER LINE NOTATION : 1Y1&OVR DOPS&O2&MY1&1 COMPOUND DESCRIPTOR : Agricultural Chemical SYNONYMS/TRADE NAMES : * 2-(O-Aethyl-N-isopropylamidothiophosphoryloxy)-benzosaeure-isopropylester * Amaze * BAY-92114 * BAY-SRA-12869 * Benzoic acid, 2-((ethoxy((1-methylethyl)amino)phosphinothioyl)oxy)-, 1-methyl ester * Discus * 2-((Ethoxy((1-methylethyl)amino)phosphinothioyl)oxy)benzoic acid 1-methylethyl ester * O-Ethyl-O-(2-isopropoxy-carbonyl)-phenyl isopropylphosphoramidothioate * Isofenphos * Isophenphos * Isopropyl salicylate O-ester with O-ethylisopropylphosphoramidothioate * LE-Mat * 1-Methylethyl-2-((ethoxy((1-methylethyl)amino)phosphinothioyl)oxy) benzoate * Oftanol * Phosphoramidothioic acid, isopropyl-, O-ethyl O-(2-isopropoxycarbonylphenyl) ester * Pyrfon * 40 SD * SRA 12869 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 28 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 1,118,1977 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 144 mg/m3/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A236,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 188 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,39,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 91300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 162 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C173,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 3 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle weakness Gastrointestinal - changes in structure or function of salivary glands REFERENCE : BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 33,386,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - quail DOSE/DURATION : 13 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 8,551,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2240 mg/kg/8W-I TOXIC EFFECTS : Liver - other changes Biochemical - Metabolism (Intermediary) - other proteins REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 21,684,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** STATUS IN U.S. *** EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***